Published in
American Association for the Advancement of Science, Science Advances, 43(6), 2020
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Supramolecular nanosubstrate–mediated delivery system enables CRISPR-Cas9 knockin of hemoglobin beta gene for hemoglobinopathies
Journal article published in 2020 by
Peng Yang 
,
Shih-Jie Chou ,
Jindian Li,
Wenqiao Hui,
Wenfei Liu ,
Na Sun ,
Ryan Y. Zhang ,
Yazhen Zhu ,
Ming-Long Tsai ,
Henkie I. Lai ,
Matthew Smalley ,
Xinyue Zhang,
Jiayuan Chen ,
Zulema Romero ,
Dahai Liu
and other authors.
,
Shih-Jie Chou ,
Jindian Li,
Wenqiao Hui,
Wenfei Liu ,
Na Sun ,
Ryan Y. Zhang ,
Yazhen Zhu ,
Ming-Long Tsai ,
Henkie I. Lai ,
Matthew Smalley ,
Xinyue Zhang,
Jiayuan Chen ,
Zulema Romero ,
Dahai Liu
and other authors.
This paper is made freely available by the publisher.
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Abstract
CRISPR-Cas9 knockin of the HBB gene paves the way for a general therapeutic solution for treating hemoglobinopathies.