Published in

American Society for Microbiology, Infection and Immunity, 1(89), 2020

DOI: 10.1128/iai.00180-20

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GigC, a LysR-family Transcription Regulator is required for cysteine metabolism and virulence in Acinetobacter baumannii

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Data provided by SHERPA/RoMEO

Abstract

A critical facet of mammalian innate immunity involves the hosts’ attempts to sequester and/or limit the availability of key metabolic products from pathogens. For example, nutritional immunity encompasses host approaches to limit the availability of key heavy metal ions such as zinc and iron. Previously, we identified several hundred genes in a multidrug-resistant isolate of Acinetobacter baumannii that are required for growth and/or survival in the Galleria mellonella infection model.