ABSTRACT We present a suite of three-dimensional, high-resolution hydrodynamic simulations that follow the evolution of a massive (107 M⊙) pressure-confined, star-forming neutral gas cloud moving through a hot intracluster medium (ICM). The main goal of the analysis is to get theoretical insight into the lifetimes and evolution of stellar systems like the recently discovered star-forming cloud SECCO 1 in the Virgo cluster of galaxies, but it may be of general interest for the study of the star-forming gas clumps that are observed in the tails of ram pressure stripped galaxies. Building up on a previous, simple simulation, we explored the effect of different relative velocity of the cloud and larger temperature of the ICM, as well as the effect of the cloud self-gravity. Moreover, we performed a simulation including star formation and stellar feedback, allowing for a first time a direct comparison with the observed properties of the stars in the system. The survivability of the cold gas in the simulated clouds is granted on time-scales of the order of 1 Gyr, with final cold gas fractions generally >0.75. In all cases, the simulated systems end up, after 1 Gyr of evolution, as symmetric clouds in pressure equilibrium with the external hot gas. We also confirm that gravity played a negligible role at the largest scales on the evolution of the clouds. In our simulation with star formation, star formation begins immediately, it peaks at the earliest times, and decreases monotonically with time. Inhomogeneous supernova explosions are the cause of an asymmetric shape of the gas cloud, facilitating the development of instabilities and the decrease of the cold gas fraction.