Published in
American Association for the Advancement of Science, Science Translational Medicine, 565(12), 2020
DOI: 10.1126/scitranslmed.abb0391
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Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti–PD-1 for patients with anti–PD-1–refractory tumors
Journal article published in 2020 by
Iván Márquez-Rodas 
,
Federico Longo ,
Maria E. Rodriguez-Ruiz,
Antonio Calles ,
Santiago Ponce ,
Maria Jove,
Rosa Álvarez ,
Jose Luis Perez-Gracia,
Belén Rubio-Viqueira ,
Ainara Soria-Rivas,
Rodriguez Ruiz Me ,
Enrique de Miguel ,
Ana Gómez-Rueda ,
Mariano Ponz-Sarvise ,
Sara López-Tarruella
and other authors.
,
Federico Longo ,
Maria E. Rodriguez-Ruiz,
Antonio Calles ,
Santiago Ponce ,
Maria Jove,
Rosa Álvarez ,
Jose Luis Perez-Gracia,
Belén Rubio-Viqueira ,
Ainara Soria-Rivas,
Rodriguez Ruiz Me ,
Enrique de Miguel ,
Ana Gómez-Rueda ,
Mariano Ponz-Sarvise ,
Sara López-Tarruella
and other authors.
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Abstract
Intratumoral BO-112 combined with systemic anti–PD-1 shows immunotherapeutic potential to control tumors in patients primarily refractory to anti–PD-1.