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American Society for Microbiology, Journal of Clinical Microbiology, 1(59), 2020

DOI: 10.1128/jcm.01749-20

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Diagnostic accuracy of four commercial triplex immunochromatographic tests for rapid detection of rotavirus, adenovirus and norovirus in human stool samples

Journal article published in 2020 by Jérôme Kaplon ORCID, Lucie Théry, Maxime Bidalot, Nadège Grangier, Jean Frappier, Ludwig Serge Aho Glélé, Alexis de Rougemont, Katia Ambert-Balay
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Noroviruses (NoV), rotaviruses (RVA), and adenoviruses (AdV) are the main viral agents responsible for acute gastroenteritis (AGE) in humans. We aimed to determine the diagnostic accuracy of four commercial immunochromatographic tests (ICTs) intended for the rapid and simultaneous detection of these three pathogens. Diagnostic accuracy of bioNexia Noro/Rota-Adeno (bioMérieux), Immunoquick NoRotAdeno (Biosynex), Rota+Adeno+Noro combo card (CerTest Biotec), and Rida Quick Rota/Adeno/Noro Combi (R-Biopharm) ICTs was assessed retrospectively using a collection of 160 stool specimens (including 43 RVA-, 47 AdV-, and 42 NoV-positive samples) from French patients with AGE and using molecular methods as the reference standard.