Published in
American Association for the Advancement of Science, Science Advances, 40(6), 2020
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The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
Journal article published in 2020 by
Riyad N. H. Seervai 
,
Rahul K. Jangid ,
Menuka Karki ,
Durga Nand Tripathi ,
Sung Yun Jung ,
Sarah E. Kearns ,
Kristen J. Verhey,
Michael A. Cianfrocco ,
Bryan A. Millis ,
Matthew J. Tyska ,
Frank M. Mason ,
W. Kimryn Rathmell ,
In Young Park ,
Ruhee Dere ,
Cheryl Lyn Walker
,
Rahul K. Jangid ,
Menuka Karki ,
Durga Nand Tripathi ,
Sung Yun Jung ,
Sarah E. Kearns ,
Kristen J. Verhey,
Michael A. Cianfrocco ,
Bryan A. Millis ,
Matthew J. Tyska ,
Frank M. Mason ,
W. Kimryn Rathmell ,
In Young Park ,
Ruhee Dere ,
Cheryl Lyn Walker
This paper is made freely available by the publisher.
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Abstract
SETD2 regulates actin dynamics and cell migration via methylation of actin at Lys 68 in a cellular complex containing Huntingtin.