Published in

Elsevier, The Lancet, 9583(370), p. 240-250, 2007

DOI: 10.1016/s0140-6736(07)61126-x

Elsevier, Year Book of Oncology, (2008), p. 259-261

DOI: 10.1016/s1040-1741(08)79184-x

Elsevier, Year Book of Pediatrics, (2009), p. 503-506

DOI: 10.1016/s0084-3954(08)79128-0

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A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.

Journal article published in 2007 by Rob Pieters, Martin Schrappe, Paola De Lorenzo, Ian Hann, Giulio De Rossi, Maria Felice, Liisa Hovi, Thierry Leblanc, Tomasz Szczepanski ORCID, Alina Ferster, Gritta Janka, Jeffrey Rubnitz ORCID, Lewis B. Silverman, Jan Stary, Myriam Campbell and other authors.
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Abstract

Acute lymphoblastic leukaemia in infants younger than 1 year is rare, and infants with the disease have worse outcomes than do older children. We initiated an international study to investigate the effects of a new hybrid treatment protocol with elements designed to treat both acute lymphoblastic leukaemia and acute myeloid leukaemia, and to identify any prognostic factors for outcome in infants. We also did a randomised trial to establish the value of a late intensification course. ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't ; SCOPUS: ar.j ; info:eu-repo/semantics/published