Published in
American Association for the Advancement of Science, Science Translational Medicine, 560(12), 2020
DOI: 10.1126/scitranslmed.aax2282
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Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade
Journal article published in 2020 by
Liangliang Wang 
,
Yan Gao,
Gao Zhang ,
Dan Li ,
Zhenda Wang,
Jie Zhang ,
Leandro C. Hermida ,
Lei He,
Zhisong Wang,
Jingwen Si ,
Shuang Geng,
Rizi Ai ,
Fei Ning,
Chaoran Cheng,
Haiteng Deng
and other authors.
,
Yan Gao,
Gao Zhang ,
Dan Li ,
Zhenda Wang,
Jie Zhang ,
Leandro C. Hermida ,
Lei He,
Zhisong Wang,
Jingwen Si ,
Shuang Geng,
Rizi Ai ,
Fei Ning,
Chaoran Cheng,
Haiteng Deng
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
The bifunctional compound D18 improves checkpoint blockade efficacy by increasing KDM5A and PD-L1 abundance and inducing TLR7/8 activation.