Abstract Changes in vegetation productivity based on normalized difference vegetation index (NDVI) have been reported from Arctic regions. Most studies use very coarse spatial resolution remote sensing data that cannot isolate landscape level factors. For example, on Yamal Peninsula in West Siberia enhanced willow growth has been linked to widespread landslide activity, but the effect of landslides on regional NDVI dynamics is unknown. Here we apply a novel satellite-based NDVI analysis to investigate the vegetation regeneration patterns of active-layer detachments following a major landslide event in 1989. We analyzed time series data of Landsat and very high-resolution (VHR) imagery from QuickBird-2 and WorldView-2 and 3 characterizing a study area of ca. 35 km². Landsat revealed that natural regeneration of low Arctic tundra progressed rapidly during the first two decades after the landslide event. However, during the past decade, the difference between landslide shear surfaces and surrounding areas remained relatively unchanged despite the advance of vegetation succession. Time series also revealed that NDVI generally declined since 2013 within the study area. The VHR imagery allowed detection of NDVI change ‘hot-spots’ that included temporary degradation of vegetation cover, as well as new and expanding thaw slumps, which were too small to be detected from Landsat satellite data. Our study demonstrates that landslides can have pronounced and long-lasting impacts on tundra vegetation. Thermokarst landslides and associated impacts on vegetation will likely become increasingly common in NW Siberia and other Arctic regions with continued warming.