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American Physiological Society, Journal of Applied Physiology, 4(129), p. 873-879, 2020

DOI: 10.1152/japplphysiol.00570.2020

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The effect of long-term ultra-endurance exercise and SOD2 genotype on telomere shortening with age

Journal article published in 2020 by Barbara Hernando, Marta Gil-Barrachina, Elena Tomas-Bort ORCID, Ignacio Martinez-Navarro ORCID, Eladio Collado-Boira, Carlos Hernando
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Habitual ultra-endurance exercise seems to promote telomere length maintenance, especially at older ages. In addition, the beneficial effect of ultra-endurance training on biological aging is higher in ultra-trail runners who have been engaged to ultra-endurance training during many years. Finally, and for the first time, this study shows that the SOD2 rs4880 polymorphism has a significant impact on telomere length, as well as on acute inflammatory response to a 107-km trail race.