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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(64), 2020

DOI: 10.1128/aac.00740-20

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Evaluation of Two Commercial Broth Microdilution Methods Using Different Interpretive Criteria for the Detection of Molecular Mechanisms of Acquired Azole and Echinocandin Resistance in Four Common Candida Species

Journal article published in 2020 by Ha Jin Lim, Jong Hee Shin ORCID, Mi-Na Kim ORCID, Dongeun Yong, Seung A. Byun, Min Ji Choi, Seung Yeob Lee, Eun Jeong Won, Seung-Jung Kee, Soo Hyun Kim, Myung-Geun Shin
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The abilities of the new Vitek 2 AST-YS08 (YS08) and Sensititre YeastOne (SYO) systems to detect the resistances of Candida isolates to azoles and echinocandins were evaluated. In total, 292 isolates, including 28 Candida albicans (6 Erg11 and 2 Fks mutants), 57 Candida parapsilosis (26 Erg11 mutants), 24 Candida tropicalis (10 Erg11 and 1 Fks mutants), and 183 Candida glabrata (39 Pdr1 and 13 Fks mutants) isolates, were tested.