Published in
American Association for the Advancement of Science, Science Translational Medicine, 559(12), 2020
DOI: 10.1126/scitranslmed.abb3774
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C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy
Journal article published in 2020 by
Casey N. Cook 
,
Yanwei Wu ,
Hana M. Odeh ,
Tania F. Gendron ,
Karen Jansen-West ,
Giulia del Rosso,
Mei Yue,
Peizhou Jiang,
Edward Gomes,
Jimei Tong,
Lillian M. Daughrity ,
Nicole M. Avendano,
Monica Castanedes-Casey ,
Wei Shao,
Björn Oskarsson
and other authors.
,
Yanwei Wu ,
Hana M. Odeh ,
Tania F. Gendron ,
Karen Jansen-West ,
Giulia del Rosso,
Mei Yue,
Peizhou Jiang,
Edward Gomes,
Jimei Tong,
Lillian M. Daughrity ,
Nicole M. Avendano,
Monica Castanedes-Casey ,
Wei Shao,
Björn Oskarsson
and other authors.
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Abstract
G 4 C 2 repeat–derived poly(GR) plays a key role in mediating TDP-43 mislocalization and aggregation in vitro and in vivo.