Published in
American Association for the Advancement of Science, Science Advances, 34(6), 2020
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Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability
Journal article published in 2020 by
Marian H. Hettiaratchi 
,
Matthew J. O’Meara ,
Teresa R. O’Meara ,
Andrew J. Pickering ,
Nitzan Letko-Khait,
Molly S. Shoichet
,
Matthew J. O’Meara ,
Teresa R. O’Meara ,
Andrew J. Pickering ,
Nitzan Letko-Khait,
Molly S. Shoichet
This paper is made freely available by the publisher.
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Abstract
Computational redesign of chondroitinase ABC introduces 37 point mutations to improve enzyme stability and activity.