Abstract The filtration of fracturing fluid is one of the important factors that affect the effect of fracturing construction. Therefore, it is of great significance to study fracturing fluid loss for fracturing technology. Based on the fracturing fluid filtration theory, the fluid loss coefficient is used to describe the loss of the fracturing fluid in the formation. At the same time, according to the different formation conditions, the corresponding pressure drop analysis model is used to describe the pressure falling process. According to a target area, the filter loss parameter is calculated by combining the filtration mechanism and the pressure drop pressure drop analysis model. It is necessary to study the fracturing fluid technology and optimize the fracturing fluid with the concentration of 4% of the filtrate reducer, which is compared with the original formula with the concentration of 1% of the original filtrate loss agent. The loss coefficient is reduced by 44.13% on average, which can better meet the actual demand.