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American Association for the Advancement of Science, Science Advances, 31(6), 2020

DOI: 10.1126/sciadv.abb0806

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IL-10–producing Tfh cells accumulate with age and link inflammation with age-related immune suppression

Journal article published in 2020 by Maha Almanan ORCID, Jana Raynor, Ireti Ogunsulire, Anna Malyshkina ORCID, Shibabrata Mukherjee, Sarah A. Hummel, Jennifer T. Ingram, Ankur Saini ORCID, Markus M. Xie ORCID, Theresa Alenghat ORCID, Sing Way ORCID, George S. Deepe ORCID, Senad Divanovic ORCID, Harinder Singh ORCID, Emily Miraldi ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Elevated IL-10 in aged mice suppresses immune responses and has implications for vaccine nonresponsiveness in the elderly.