Published in
American Association for the Advancement of Science, Science Immunology, 49(5), 2020
DOI: 10.1126/sciimmunol.aaw2262
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T <sub>H</sub> 17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity
Journal article published in 2020 by
Stacey N. Harbour 
,
Daniel F. DiToro,
Steven J. Witte ,
Carlene L. Zindl ,
Min Gao,
Trenton R. Schoeb ,
Gareth W. Jones ,
Simon A. Jones ,
Robin D. Hatton ,
Casey T. Weaver
,
Daniel F. DiToro,
Steven J. Witte ,
Carlene L. Zindl ,
Min Gao,
Trenton R. Schoeb ,
Gareth W. Jones ,
Simon A. Jones ,
Robin D. Hatton ,
Casey T. Weaver
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Abstract
Ongoing classic IL-6 receptor signaling is required to maintain the T H 17 program, acting upstream of IL-23 to sustain RORγt expression.