This paper discussed mentoring, a tool for successful collaboration for Library and Information Science (LIS) educators, in the University of Calabar. For reasons why LIS educators collaborate, respondents revealed, among others, a sense of belonging, motivation, the challenge of management, witch-hunting, and reduction of cost of conducting research, among others. The results from mentoring for collaboration indicated that 19 respondents published 8 articles out of their first 11 published articles through collaboration efforts. Six respondents published six and two respondents had four through collaborative efforts. These represented 70.4%, 22.2%, and 7.41% of the results of mentoring for collaboration. The result show that LIS senior educators mentor young academics for collaboration. The paper identified some challenges of mentoring and the researcher suggested that mentors should be straightforward with the mentees because it is only by trust that people can work together irrespective of their profession.