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Royal Society of Chemistry, RSC Advances, 43(10), p. 25557-25566, 2020

DOI: 10.1039/d0ra02574g

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Efficient modification of PAMAM G1 dendrimer surface with β-cyclodextrin units by CuAAC: impact on the water solubility and cytotoxicity

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The toxicity of the poly(amidoamine) dendrimers (PAMAM) caused by the peripheral amino groups has been a limitation for their use as drug carriers in clinical applications.