ABSTRACT Objectives: to validate nursing interventions for the diagnosis Risk for Impaired Skin Integrity in adult and aged hospitalized patients. Methods: descriptive, quantitative study, using the content validity of interventions done by 14 specialist nurses. Results: the specialist nurses had worked in the area for more than five years. Four (28.5%) used NANDA-I and CIPE®, three (21.4%) used NANDA-I, NIC and CIPE®, three (21.4%) used NANDA-I, NIC, NOC and CIPE® and four (28.5%) were currently working only with CIPE®. The validation analyzed 32 NIC interventions, of which 11 were priority and 21 were suggested. Of the priority interventions, five belonged to the Physiological/Complex domain, five to the Physiological/Basic domain and one to the Safety Domain. Final Considerations: nursing interventions are essential for planning and support good practices in teaching, research and care.