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American Association for the Advancement of Science, Science Advances, 25(6), 2020

DOI: 10.1126/sciadv.abb2210

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Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

Journal article published in 2020 by Anne Fassl ORCID, Christopher Brain, Monther Abu-Remaileh, Iga Stukan, Deborah Butter, Piotr Stepien, Avery S. Feit, Johann Bergholz, Wojciech Michowski, Tobias Otto ORCID, Qing Sheng ORCID, Alice Loo, Walter Michael, Ralph Tiedt, Carmine DeAngelis and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This study presents strategies to render triple-negative breast cancers sensitive to CDK4/6 inhibitors.