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Oxford University Press (OUP), European Journal of Cardio-Thoracic Surgery, 6(41), p. e173-e181

DOI: 10.1093/ejcts/ezs170

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High expression of octamer-binding transcription factor 4A, prominin-1 and aldehyde dehydrogenase strongly indicates involvement in the initiation of lung adenocarcinoma resulting in shorter disease-free intervals

Journal article published in 2012 by Lourdes Cortes-Dericks, Domenico Galetta, Lorenzo Spaggiari, Ralph Alexander Schmid ORCID, Golnaz Karoubi
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The increasing relevance of the cancer stem cell (CSC) hypothesis and the impact of CSC-associated markers in the carcinogenesis of solid tumours may provide potential prognostic implications in lung cancer. We propose that a collective genetic analysis of established CSC-related markers will generate data to better define the role of putative CSCs in lung adenocarcinoma (LAC).