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Royal Society of Chemistry, RSC Advances, 40(10), p. 23668-23674, 2020

DOI: 10.1039/d0ra01803a

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Automated glycan assembly of Streptococcus pneumoniae type 14 capsular polysaccharide fragments

Journal article published in 2020 by João Louçano, Peter Both, Andrea Marchesi ORCID, Linda del Bino, Roberto Adamo ORCID, Sabine Flitsch ORCID, Mario Salwiczek ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A streamlined automated synthesis for S. pneumoniae type 14 and Group B Streptococcus type III capsular oligosaccharides with only one set of three building blocks is presented. Competitive ELISA provides some insight into minimal epitope.