Published in

SAGE Publications, Journal of Pharmacology and Pharmacotherapeutics, 2(5), p. 163-165, 2014

DOI: 10.4103/0976-500x.130110

Links

Tools

Export citation

Search in Google Scholar

A case of tinnitus induced by chlorpromazine in a pediatric patient

Journal article published in 2014 by Carla Carnovale ORCID, Silvia Beretta, Paolo Pellegrino, Stefania A. Antoniazzi, Sonia Radice, GianVincenzo V. Zuccotti ORCID, Valentina Perrone, Marco Pozzi, Emilio G. I. Clementi
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Chlorpromazine is a well-known antipsychotic agent that binds with a variety of receptors in the central nervous system. To date, chlorpromazine has never been associated with onset of hearing disorders and tinnitus. We report on an unexpected suspect adverse reaction to chlorpromazine that occurred in a 12-year-old boy, affected by severe generalized anxiety disorder. After treatment with chlorpromazine, the patient experienced an enhanced sensitivity to sounds accompanied by perception of noises of the buzzing or ringing type. This clinical case is of great clinical interest as chlorpromazine is not currently included among potentially ototoxic drugs.