Published in
Royal Society of Chemistry, Chemical Science, 27(11), p. 7023-7030, 2020
DOI: 10.1039/d0sc02393k
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Switchable foldamer ion channels with antibacterial activity
Journal article published in 2020 by
Anna D. Peters,
Stefan Borsley,
Flavio della Sala 
,
Dominic F. Cairns-Gibson,
Marios Leonidou,
Jonathan Clayden ,
George F. S. Whitehead ,
Iñigo J. Vitórica-Yrezábal ,
Eriko Takano ,
John Burthem ,
Scott L. Cockroft ,
Simon J. Webb
,
Dominic F. Cairns-Gibson,
Marios Leonidou,
Jonathan Clayden ,
George F. S. Whitehead ,
Iñigo J. Vitórica-Yrezábal ,
Eriko Takano ,
John Burthem ,
Scott L. Cockroft ,
Simon J. Webb
This paper is made freely available by the publisher.
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Abstract
Triazole-capped α-aminoisobutyric acid (Aib) octameric foldamers formed very active ion channels in phospholipid bilayers after the addition of copper(ii) chloride, with activity “turned off” by copper(ii) extraction.