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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 8(64), 2020

DOI: 10.1128/aac.00900-20

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Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic that originated in Wuhan, China, in December 2019 has impacted public health, society, the global economy, and the daily lives of billions of people in an unprecedented manner. There are currently no specific registered antiviral drugs to treat or prevent SARS-CoV-2 infections. Therefore, drug repurposing would be the fastest route to provide at least a temporary solution while better, more specific drugs are being developed.