The aims of this study were to describe the external and internal workloads in a professional female futsal team during a whole season and to compare workloads during different periods of the season. Ten professional female futsal players (age 22.8 ± 4.3 years; 5.1 ± 2.4 years of experience; weight 61.9 ± 7.1 kg; height 1.66 ± 0.06 m) participated voluntarily in this study during the whole season. The internal workload was measured by the session-Rate of perceived exertion (session-RPE) method, while the external workload was indirectly measured by considering the training and match volume and the type of contents of each session over 43 weeks. Mean sRPE throughout the season was 319.9 ± 127.1 arbitrary units (AU). Higher internal loads (total weekly training load and strain) were reported during the pre-season compared with the in-season mesocycles (p < 0.05); meanwhile, the fifth to eighth mesocycles of the in-season showed an oscillatory pattern. Finally, Monday was the most-demanding session during the in-season period over the Thursday (p < 0.05; effect size: 1.33) followed by match day, meanwhile no statistical differences were reported during different sessions of the pre-season microcycle (p > 0.05). This study suggests that microcycles of pre-season present a stable load pattern, meanwhile workloads during the in-season period report a tapering strategy in a professional female futsal team.