We write an open letter to the NIH Data Research Council to initiate a dialog regarding NIH decisions on data use agreements and licenses. We are members of NIH-funded research groups that collect and/or integrate biomedical data from diverse sources for the purpose of advancing diagnosis, prognosis, treatment selection, and mechanistic discovery. We welcome additional signatories here:https://docs.google.com/document/d/1fbwKxnPu5f1YXlMM6UMyfBqHx_Inz86tKzwRFO4W8jQSummary:The current diversity of data use agreements and licenses significantly hampers the ability to reuse and redistribute data in various informatics contexts.We believe that any mandatory data licensing policy must also include a plan for ensuring access, sustainability, and data quality. We request community partnership with NIH to develop common licensing and data reuse plans.