Published in
American Association for the Advancement of Science, Science Translational Medicine, 545(12), 2020
DOI: 10.1126/scitranslmed.aaz5387
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Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases
Journal article published in 2020 by
Lin Zhang 
,
Jun Yao ,
Yongkun Wei,
Zhifen Zhou ,
Ping Li,
Jingkun Qu,
Akosua Badu-Nkansah ,
Xiangliang Yuan ,
Yu-Wen Huang,
Kazutaka Fukumura ,
Xizeng Mao,
Wei-Chao Chang,
Jodi Saunus ,
Sunil Lakhani ,
Jason T. Huse
and other authors.
,
Jun Yao ,
Yongkun Wei,
Zhifen Zhou ,
Ping Li,
Jingkun Qu,
Akosua Badu-Nkansah ,
Xiangliang Yuan ,
Yu-Wen Huang,
Kazutaka Fukumura ,
Xizeng Mao,
Wei-Chao Chang,
Jodi Saunus ,
Sunil Lakhani ,
Jason T. Huse
and other authors.
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Abstract
G-CSF antibodies and immune checkpoint blockade with Src inhibitors block neutrophil infiltration to impede pY696-EZH2–driven brain metastasis.