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American Association for the Advancement of Science, Science Advances, 21(6), 2020

DOI: 10.1126/sciadv.aba2983

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CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation

Journal article published in 2020 by Wujin Sun ORCID, Jinqiang Wang ORCID, Quanyin Hu, Xingwu Zhou, Ali Khademhosseini ORCID, Zhen Gu ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A DNA-based bioresponsive nanoformulation delivers the CRISPR-Cas12a to hepatocytes for regulating serum cholesterol.