Chrysolaena glandulosa is a new species of Vernonieae (Asteraceae), endemic to the “campos rupestres” of Serra da Canastra National Park and adjacent areas of southwestern Minas Gerais state, Brazil. Chrysolaena glandulosa is characterized by its laxly disposed leaves and lower surface with glandular dots, corolla lobes papillose with glandular dots, and strigose achenes with glandular dots. It is morphologically similar to C. campestris but differs from the latter by presence of glandular dots on the lower surface of the leaves, the ratio between the size of the bracts of the inflorescence and the involucre, and the number of heads and flowers per head. Pollen study confirms that this species belongs to Chrysolaena. A diagnostic key is presented to all Minas Gerais species.