Published in
Oxford University Press, Metallomics, 5(12), p. 649-653, 2020
DOI: 10.1039/d0mt00070a
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Peptide bond cleavage in the presence of Ni-containing particles
Journal article published in 2020 by
Nina Ewa Wezynfeld 
,
Tomasz Frączyk ,
Arkadiusz Bonna ,
Wojciech Bal
,
Tomasz Frączyk ,
Arkadiusz Bonna ,
Wojciech Bal
This paper is made freely available by the publisher.
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Abstract
Abstract NiO nanoparticles and non-stoichiometric black NiO were shown to be effective sources of Ni2+ ions causing sequence-selective peptide bond hydrolysis. NiO nanoparticles were as effective in this reaction as their molar equivalent of soluble Ni(ii) salt. These findings highlight the efficacy of delivery of toxic Ni2+ by these environmentally available particles.