Published in
American Association for the Advancement of Science, Science Translational Medicine, 527(12), 2020
DOI: 10.1126/scitranslmed.aax1501
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The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas
Journal article published in 2020 by
Ricardo Gargini 
,
Berta Segura-Collar ,
Beatriz Herránz ,
Vega García-Escudero ,
Andrés Romero-Bravo ,
Felipe J. Núñez ,
Daniel García-Pérez ,
Jacqueline Gutiérrez-Guamán ,
Angel Ayuso-Sacido,
Joan Seoane ,
Angel Pérez-Núñez ,
Juan M. Sepúlveda-Sánchez,
Aurelio Hernández-Laín ,
María G. Castro ,
Ramón García-Escudero
and other authors.
,
Berta Segura-Collar ,
Beatriz Herránz ,
Vega García-Escudero ,
Andrés Romero-Bravo ,
Felipe J. Núñez ,
Daniel García-Pérez ,
Jacqueline Gutiérrez-Guamán ,
Angel Ayuso-Sacido,
Joan Seoane ,
Angel Pérez-Núñez ,
Juan M. Sepúlveda-Sánchez,
Aurelio Hernández-Laín ,
María G. Castro ,
Ramón García-Escudero
and other authors.
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Abstract
TAU is expressed in the less aggressive gliomas where it impairs the mesenchymal transdifferentiation of tumor cells and normalizes the vasculature.