Published in

Rockefeller University Press, Journal of Cell Biology, 6(219), 2020

DOI: 10.1083/jcb.201702151

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TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Shang et al. (2016. J. Cell Biol.https://doi.org/10.1083/jcb.201603081) reported that activation of lysosomal TRPA1 channels led to intracellular calcium transients and CGRP release from DRG neurons. We argue that both findings are more likely due to influx of insufficiently buffered extracellular calcium rather than lysosomal release.