Published in
Oxford University Press, Journal of Travel Medicine, 6(27), 2020
DOI: 10.1093/jtm/taaa034
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A case of acute generalized exanthematous pustulosis caused by exposure to Atovaquone/proguanil
Journal article published in 2020 by
Marta Arsuaga,
Rosa de Miguel 
,
Elena Trigo,
Pablo Barreiro,
Fernando de la Calle ,
Eloy José Tarin,
D. Loli-Ausejo,
Marta Diaz
,
Elena Trigo,
Pablo Barreiro,
Fernando de la Calle ,
Eloy José Tarin,
D. Loli-Ausejo,
Marta Diaz
This paper is made freely available by the publisher.
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Abstract
We present a returning traveler with acute generalized exanthematous pustulosis after atovaquone/proguanil prophylaxis. Diagnosis was confirmed with biopsy and allergy testing, symptoms resolved after steroid treatment. Atovaquone/proguanil prophylaxis is generally well tolerated, however, some patients may present severe adverse events that require prompt medical evaluation and treatment.