Published in
American Association for the Advancement of Science, Science Translational Medicine, 541(12), 2020
DOI: 10.1126/scitranslmed.aaz2481
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Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors
Journal article published in 2020 by
Erica Banks 
,
Michael Grondine ,
Deepa Bhavsar,
Evan Barry,
Jason G. Kettle ,
Venkatesh Pilla Reddy ,
Crystal Brown ,
Haiyun Wang,
Jerome T. Mettetal ,
Teresa Collins ,
Oladipupo Adeyemi ,
Ross Overman ,
Deborah Lawson ,
Alexander R. Harmer ,
Corinne Reimer
and other authors.
,
Michael Grondine ,
Deepa Bhavsar,
Evan Barry,
Jason G. Kettle ,
Venkatesh Pilla Reddy ,
Crystal Brown ,
Haiyun Wang,
Jerome T. Mettetal ,
Teresa Collins ,
Oladipupo Adeyemi ,
Ross Overman ,
Deborah Lawson ,
Alexander R. Harmer ,
Corinne Reimer
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
AZD3229 demonstrates pan-KIT/PDGFRα activity in several preclinical models and is a promising agent for the treatment of GIST.