Published in
Oxford University Press, Open Forum Infectious Diseases, 5(7), 2020
DOI: 10.1093/ofid/ofaa138
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Practicing Antimicrobial Stewardship: De-escalating Antibiotics in Patients with Acute Myeloid Leukemia and Neutropenic Fever
Journal article published in 2020 by
Risa Fuller 
,
Erin Moshier,
Samantha E. Jacobs,
Jacobs Se,
Douglas Tremblay,
Guido Lancman,
Alexander Coltoff,
Jessica Caro,
John Mascarenhas,
Meenakshi Rana
,
Erin Moshier,
Samantha E. Jacobs,
Jacobs Se,
Douglas Tremblay,
Guido Lancman,
Alexander Coltoff,
Jessica Caro,
John Mascarenhas,
Meenakshi Rana
This paper is made freely available by the publisher.
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Abstract
Abstract We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.