Published in
American Association for the Advancement of Science, Science Translational Medicine, 531(12), 2020
DOI: 10.1126/scitranslmed.aaw6471
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Anti–PD-1 treatment impairs opioid antinociception in rodents and nonhuman primates
Journal article published in 2020 by
Zilong Wang 
,
Changyu Jiang ,
Qianru He ,
Megumi Matsuda ,
Qingjian Han,
Kaiyuan Wang,
Sangsu Bang ,
Huiping Ding ,
Mei-Chuan Ko ,
Ru-Rong Ji
,
Changyu Jiang ,
Qianru He ,
Megumi Matsuda ,
Qingjian Han,
Kaiyuan Wang,
Sangsu Bang ,
Huiping Ding ,
Mei-Chuan Ko ,
Ru-Rong Ji
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Abstract
PD-1 regulates opioid signaling in primary sensory and spinal cord neurons and plays a critical role in opioid antinociception.