Reliable data regarding the usage patterns of personal care products (PCPs) are needed to determine the health risks posed by the ingredients of these products such as parabens, phthalates, and bisphenol A. There are no published data regarding the consumption patterns of PCPs in the Middle East in general and in Saudi Arabia in particular. To fill this gap, this study aimed to assess important factors such as the percentage of users and the frequency of use and co-use of twenty-three cosmetic and PCPs among the female population in Saudi Arabia. Additionally, this study aimed to assess the common cosmetic-related adverse events among the participants. The studied products included general hygiene, hair care, skin care, makeup, fragrances, and other products. The data were collected from 709 female participants of different age groups through a digital questionnaire. It was found that eighteen of the investigated products are consumed by at least 50% of the respondents. The frequency of use of PCPs varied over a wide range. Cosmetic-related adverse events were experienced by 16.1% of the participants. Use frequencies of many hygiene and makeup products were correlated with each other. This study provides, for the first time, baseline data on the usage patterns of a large number of widely consumed PCPs among female population pertaining to several sociodemographic strata. Such information is crucial for exposure and risk assessment and also needed for updating the current knowledge on usage of PCPs in Saudi Arabia.