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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 6(64), 2020

DOI: 10.1128/aac.00142-20

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Transferable Resistance Gene optrA in Enterococcus faecalis from Swine in Brazil

Journal article published in 2020 by Lara M. Almeida ORCID, François Lebreton, Anthony Gaca, Paulo M. Bispo, Jose T. Saavedra, Rodrigo N. Calumby, Luciano M. Grillo ORCID, Ticiano G. Nascimento ORCID, Pedro H. Filsner, Andrea M. Moreno ORCID, Michael S. Gilmore
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

OptrA is an ATP-binding cassette (ABC)-F protein that confers resistance to oxazolidinones and phenicols and can be either plasmid-encoded or chromosomally encoded. Here, we isolated 13 Enterococcus faecalis strains possessing a linezolid MIC of ≥4 mg/liter from nursery pigs in swine herds located across Brazil. Genome sequence comparison showed that these strains possess optrA in different genetic contexts occurring in 5 different E. faecalis sequence type backgrounds.