Published in
Royal Society of Chemistry, RSC Advances, 21(10), p. 12384-12394, 2020
DOI: 10.1039/d0ra00287a
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Carbamoyl-N-aryl-imine-urea: a new framework to obtain a putative leishmanicidal drug-candidate
Journal article published in 2020 by
Marina A. Alves,
Aline C. de Queiroz 
,
Anderson Brandão Leite,
Felipe T. Martins ,
Antonio C. Doriguetto,
Eliezer J. Barreiro,
Magna S. Alexandre-Moreira,
Lídia M. Lima
,
Anderson Brandão Leite,
Felipe T. Martins ,
Antonio C. Doriguetto,
Eliezer J. Barreiro,
Magna S. Alexandre-Moreira,
Lídia M. Lima
This paper is made freely available by the publisher.
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Abstract
LASSBio-1736 was identified as a new antileishmanial drug-candidate bearing an original framework and displaying plasma stability, cytotoxicity against amastigote forms of Leishmania species and leishmanicidal activity in a cutaneous leishmaniasis murine model.