Published in
Royal Society of Chemistry, Chemical Science, 12(11), p. 3332-3344, 2020
DOI: 10.1039/d0sc00906g
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Unravelling the effect ofN(ε)-(carboxyethyl)lysine on the conformation, dynamics and aggregation propensity of α-synuclein
Journal article published in 2020 by
Laura Mariño 
,
Rafael Ramis ,
Rodrigo Casasnovas ,
Joaquín Ortega-Castro ,
Bartolomé Vilanova ,
Juan Frau ,
Miquel Adrover
,
Rafael Ramis ,
Rodrigo Casasnovas ,
Joaquín Ortega-Castro ,
Bartolomé Vilanova ,
Juan Frau ,
Miquel Adrover
This paper is made freely available by the publisher.
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Abstract
We study the effect of an advanced glycation end product (N(ε)-(carboxyethyl)lysine), found on the Lewy bodies of people suffering from Parkinson’s disease, on the conformational and aggregation features of alpha-synuclein.