Published in
American Association for the Advancement of Science, Science Translational Medicine, 515(11), 2019
DOI: 10.1126/scitranslmed.aax2945
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Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis
Journal article published in 2019 by
Yi-Ling Chen 
,
Danuta Gutowska-Owsiak ,
Clare S. Hardman ,
Melanie Westmoreland,
Teena MacKenzie,
Liliana Cifuentes,
Dominic Waithe ,
Antonia Lloyd-Lavery ,
Allison Marquette,
Marco Londei,
Graham Ogg
,
Danuta Gutowska-Owsiak ,
Clare S. Hardman ,
Melanie Westmoreland,
Teena MacKenzie,
Liliana Cifuentes,
Dominic Waithe ,
Antonia Lloyd-Lavery ,
Allison Marquette,
Marco Londei,
Graham Ogg
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Abstract
First-in-class clinical trial of IL-33 blockade shows inhibition of neutrophil migration into human skin and modulates atopic dermatitis symptoms.