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Oxford University Press (OUP), Bioinformatics, 8(25), p. 1091-1093

DOI: 10.1093/bioinformatics/btp101

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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Journal article published in 2009 by Gabriela Bindea, Bernhard Mlecnik, Hubert Hackl, Pornpimol Charoentong, Marie Tosolini ORCID, Amos Kirilovsky, Wolf–Herman-H. Fridman, Franck Pagès, Zlatko Trajanoski, Jérôme Galon
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Summary: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.