Informal social support from family and friends has often been highlighted as the key form of support for migrants under different forms of transnational movement, particularly for female migrants. Drawing on the findings from qualitative and quantitative studies on Filipino and Indonesian migrant domestic workers in Hong Kong, this article applies the intersectionality framework to explore how migrant domestic workers approach different forms of support systems based on their multiple identities of gender, ethnicity, and religion. A clear distinction on help-seeking behavior is drawn between approaching formal and informal support systems with migrant domestic workers directly approaching formal support when the problem is employment related but turning to informal support when having emotional needs. Such distinction is found to be related to migrant domestic workers’ perceptions toward gender role and religious practices under transnational movements.