We report cosmic ray ionization rates toward ten reddened stars studied within the framework of the EDIBLES (ESO Diffuse Interstellar Bands Large Exploration Survey) program, using the VLT-UVES. For each sightline, between two and ten individual rotational lines of OH⁺ have been detected in its (0,0) and (1,0) A³Π − X³Σ⁻ electronic band system. This allows constraining of OH⁺ column densities toward different objects. Results are also presented for 28 additional sightlines for which only one or rather weak signals are found. An analysis of these data makes it possible to derive the primary cosmic ray ionization rate ζ_p in the targeted diffuse interstellar clouds. For the ten selected targets, we obtain a range of values for ζ_p equal to (3.9–16.4) × 10⁻¹⁶ s⁻¹. These values are higher than the numbers derived in previous detections of interstellar OH⁺ in the far-infrared/submillimeter-wave regions and in other near-ultraviolet studies. This difference is a result of using new OH⁺ oscillator strength values and a more complete picture of all relevant OH⁺ formation and destruction routes (including the effect of proton recombinations on PAHs), and the relatively high N(OH⁺) seen toward those ten targets.