American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 3(64), 2020
DOI: 10.1128/aac.01984-19
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Ethionamide has proven efficacy against both drug-susceptible and some drug-resistant strains of Mycobacterium tuberculosis . Limited information on its pharmacokinetics in children is available, and current doses are extrapolated from weight-based adult doses. Pediatric doses based on more robust evidence are expected to improve antituberculosis treatment, especially in small children.