Published in
Royal Society of Chemistry, Chemical Science, 7(11), p. 1985-1990, 2020
DOI: 10.1039/c9sc04916a
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An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability
Journal article published in 2020 by
Zhihe Qing 
,
Jinlei Hu,
Jingyuan Xu,
Zhen Zou ,
Yanli Lei,
Taiping Qing ,
Ronghua Yang
,
Jinlei Hu,
Jingyuan Xu,
Zhen Zou ,
Yanli Lei,
Taiping Qing ,
Ronghua Yang
This paper is made freely available by the publisher.
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Abstract
An intramolecular catalytic hairpin assembly is implemented on a DNA tetrahedron for mRNA imaging in living cells. The spatial confinement effect enables the acceleration of target-triggered signal generation, with excellent cell permeability and FRET signal stability.