Abstract Based on the technology of molecular multidimensional IR- synchrotron visualization, the paper explores integration of a new generation of biomimetic composites that regenerates a mineral organic dental enamel complex with native human hard dental tissues and dental cement. The data of spectral molecular visualization was obtained from the area of the healthy hard tissue (enamel/dentine) – biomimetic transition layer – dental material/adhesive interface. The resulting data is indicative of chemical differentiation of functional groups of all the materials at the biomimetic system/natural hard tissue and prove the chosen method to be effective in analyzing integration of dental concrete and new generation biomimetic composites.