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Royal Society of Chemistry, Chemical Science, 5(11), p. 1216-1225, 2020

DOI: 10.1039/c9sc05586j

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Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery

Journal article published in 2020 by Christine N. Morrison ORCID, Kathleen E. Prosser, Ryjul W. Stokes ORCID, Anna Cordes, Nils Metzler-Nolte ORCID, Seth M. Cohen ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Fragment-based drug discovery (FBDD) using 3-dimensional metallofragments is a new strategy for the identification of bioactive molecules.