Published in
American Association for the Advancement of Science, Science Immunology, 35(4), 2019
DOI: 10.1126/sciimmunol.aaw6647
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A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection
Journal article published in 2019 by
Nurgun Kose,
Julie M. Fox 
,
Gopal Sapparapu ,
Robin Bombardi,
Rashika N. Tennekoon ,
A. Dharshan de Silva ,
Sayda M. Elbashir ,
Matthew A. Theisen ,
Elisabeth Humphris-Narayanan ,
Giuseppe Ciaramella ,
Sunny Himansu ,
Michael S. Diamond ,
James E. Crowe
,
Gopal Sapparapu ,
Robin Bombardi,
Rashika N. Tennekoon ,
A. Dharshan de Silva ,
Sayda M. Elbashir ,
Matthew A. Theisen ,
Elisabeth Humphris-Narayanan ,
Giuseppe Ciaramella ,
Sunny Himansu ,
Michael S. Diamond ,
James E. Crowe
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Abstract
Lipid nanoparticles containing mRNA encoding a human antibody for chikungunya virus protect against infection and arthritis.